As a precautionary measure, the Chemilift concept advocates a concentration of phenol between 30% and 35%, producing a decrease in toxicity.
New: Phenol + Transcutol® (<1%) = intradermal remanence.
Several authors recommend using croton oil as a penetration agent. The drawbacks of croton oil are well known and good judgment recommends another penetration agent, Transcutol®. This penetration agent has a reservoir effect. Its action creates an effect of dermal remanence and, as a result, a prolonged action of phenol without an increase in intrinsic toxicity. It is monoethylic ether of diethylene glycol.